QDOSE® Multi-purpose Voxel Dosimetry (Personalized Dosimetry in Molecular Radiotherapy). USFDA 510(k) clearance granted in August 2023.

Multi-purpose Molecular Imaging Dosimetry Software

QDOSE® Multi-purpose Voxel Dosimetry (Personalized Dosimetry in Molecular Radiotherapy) provides state-of-the-art assessment of radiation absorbed dose to organs and tissues of the body from medically administered radiopharmaceuticals. This software is a complete, one-stop solution for all internal dosimetry needs with multiple parallel workflows. 

Multiple time points from 2D conjugate—view imaging. Quantitative methods according to MIRD recommendations.

Multiple time points from 2D conjugate views plus quantitative SPECT/CT for data point calibration.

Multiple registered time points for quantitative SPECT/CT or PET/CT imaging. 

Tool for selective internal radiation therapy using yttrium-90 microspheres for hepatocellular carcinoma. Post-treatment single-time-point yttrium-90 PET/CT or bremsstrahlung SPECT/CT. Evaluations using a Tc-99m-macroagregated albumin SPECT/CT scan. 

Safety & Efficacy Dosimetry at the Same Time

QDOSE® features fully automated organ segmentation, single time-point dosimetry, and one-click hybrid dosimetry capabilities, supported by algorithms for fast data processing and an extensive radionuclide database. Integrated with IDAC-DOSE2.1, QDOSE® provides reliable estimates of organ absorbed dose and effective dose for clinical applications in nuclear medicine and molecular radiotherapy.

The Complete One-Stop Dosimetry Software

  • Versatile nuclear medicine imaging interface 
  • DICOM and data import utility from planar scintigraphy, SPECT, PET, CT and MRI
  • Rigid and deformable 3D coregistration
  • Automated and semi-automated segmentation
  • Automated organ coregistration
  • Iterative curve fitting
  • Configurable output reporting
  • Organ overlap correction

Designed & Developed by Practitioners

QDOSE® was developed by ABX-CRO (Dresden, Germany) in collaboration with Quantinm AB (Stockholm, Sweden). Since its inception, QDOSE® has been MDD & MDR certified. This is a testament to its quality and compliance since 2017. QDOSE+ is the progressive evolution and enriched iteration of its predecessor, embracing enhanced features and capabilities. 

Dose-volume histogram from QDOSE® software.


QDOSE® is intended to estimate the absorbed dose to organs based on intracorporal administration of radiopharmaceuticals in patients with cancer. It is used by radiologists, nuclear medicine physicians, and medical physicists.

Data Import and Management
Importing data is easy in QDOSE®. Data folders can easily be scanned for images that are sorted automatically and receive recursive folder support with energy and head consistency checks. If anything in the import is missed, the software allows for retrospective image adding, and specification of image units and calibration factors, with an easy overview and editing of metadata. QDOSE® also includes DICOM import of NM/PET/CT and MRI.
Multiple Parallel Workflows
In QDOSE®, users can decide on either single or parallel workflows, depending on what data they've made available and loaded into the software. This workflow freedom optimizes management of PRRT treatment methods and SIRT treatments. Whether you need Single Time Point Dosimetry or if you are using time activity curves, QDOSE® has the functionality for it all in just a few clicks.
Rigid and Deformable Image Coregistration
Regardless of dosimetry method used (2D, 2.5D or 3D), QDOSE® provides a coregistration method to minimize image and organ displacements. This includes automatic and manual rigid 2D coregistration on whole body and organ level, dedicated 2D coregistration of reference (e.g. vial), automatic (rigid and deformable) and manual rigid 3D coregistration between time points based on CT, and automatic and manual rigid 3D coregistration between SPECT/PET and CT/MRI for the same time point.
Powerful Curve Fitting Package
The comprehensive and flexible curve fitting package provided in QDOSE provides the user with a wide range of functionality, including exclusion of data points (outliers), SPECT calibration factor for hybrid methodology, and Mono-, bi-, or tri-exponential fit to Time Activity Curves (TAC).
Advanced Drawing and Segmentation
QDOSE® allows multiple possibilities for ROI and VOI boundary drawing on planars, SPECT, CT, or fused data. Included in these options are drawing (freehand, polygon, ellipse) and editing of regions in 2D and 3D, separated handling of volume and activity regions in 3D, and several segmentation paths (ROI/VOI, fuzzy logic cluster, region growing).
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